SYNERGOLAB - evidence based nature

YXOR™ cream gel
contains 21 different active ingredients with proven,
synergistic effects,
including plant extracts
and a significant amount of
skin care substances and
skin absorption enhancers.

Learn more >

YXOR™ cream gel
contains 21 different active ingredients with proven,
synergistic effects,
including plant extracts
and a significant amount of
skin care substances and
skin absorption enhancers.

Learn more >

43%

43%

YXOR™ is a scientifically
formulated, natural pain-relieving
and anti-inflammatory
cream gel with over
43% active ingredient content.

Learn more >

Freedom of
movement

most of the time
we only appreciate it when we lose it!

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who is YXOR™ recommended for?>

Methyl salicylic acid

Plants containing salicylic acid have been used for centuries to reduce pain and inflammation. The methyl salicylic acid in the essential oil of wintergreen was successfully used to produce salicylic acid as early as 1844. 1

Methyl salicylic acid is a colourless, sweet-smelling, viscous compound. Pharmacological and clinical studies have shown that methyl salicylate is converted to salicylic acid in the body. It is used topically as a cream to treat acute pain. 2

1 Kazutami Sakamoto, et al, Cosmetic Science and Technology: Theoretical Principles and Applications „Topical analgesics introduction”. Medicine. ox.ac.uk. 2003-05-26. Archived from the original on 2012-08-04. Retrieved 2012-11-07.

2 Mason, L.; Moore, R. A.; Edwards, J. E.; McQuay, H. J.; Derry, S.; Wiffen, P. J. (2004). „Systematic review of efficacy of topical rubefacients containing salicylates for the treatment of acute and chronic pain”. British Medical Journal. 328 (7446): 995.

Methyl salicylic acid

Plants containing salicylic acid have been used for centuries to reduce pain and inflammation. The methyl salicylic acid in the essential oil of wintergreen was successfully used to produce salicylic acid as early as 1844. 1

Methyl salicylic acid is a colourless, sweet-smelling, viscous compound. Pharmacological and clinical studies have shown that methyl salicylate is converted to salicylic acid in the body. It is used topically as a cream to treat acute pain. 2

1 Kazutami Sakamoto, et al, Cosmetic Science and Technology: Theoretical Principles and Applications „Topical analgesics introduction”. Medicine. ox.ac.uk. 2003-05-26. Archived from the original on 2012-08-04. Retrieved 2012-11-07.

2 Mason, L.; Moore, R. A.; Edwards, J. E.; McQuay, H. J.; Derry, S.; Wiffen, P. J. (2004). „Systematic review of efficacy of topical rubefacients containing salicylates for the treatment of acute and chronic pain”. British Medical Journal. 328 (7446): 995.

Celadrin

A natural combination of cetylated fatty acid esters. Cetylated fatty acids are naturally occurring fats. YXOR™ cream gel contains a blend of these cetylated fatty acids in natural proportions.

In recent years, cetyl myristoleate has received the most attention, as it has been demonstrated in numerous studies that it has pain-relieving and anti-inflammatory effects in various joints when used as a cream, either alone or in combination with menthol. 1

1 William J. et Al. A Cetylated Fatty Acid Topical Cream With Menthol Reduces Pain and Improves FunctionalPerformance In Individuals with Arthritis Journal of Strength and Conditioning Research, 2005, 19(2), 475–480

Celadrin

A natural combination of cetylated fatty acid esters. Cetylated fatty acids are naturally occurring fats. YXOR™ cream gel contains a blend of these cetylated fatty acids in natural proportions.

In recent years, cetyl myristoleate has received the most attention, as it has been demonstrated in numerous studies that it has pain-relieving and anti-inflammatory effects in various joints when used as a cream, either alone or in combination with menthol. 1

1 William J. et Al. A Cetylated Fatty Acid Topical Cream With Menthol Reduces Pain and Improves Functional Performance In Individuals with Arthritis Journal of Strength and Conditioning Research, 2005, 19(2), 475–480

Comfrey root extract

The comfrey is a perennial native plant in Europe and Asia. It is very widespread throughout Europe, including Hungary.

It particularly likes moist soil. Both its root and the leaves are used for medicinal purposes. It has been shown to contain a number of active substances, including alkaloids, carbohydrates, triterpenes, tannins, allantoin, organic acids, and vitamins A and B12.

The European Medicines Agency (EMA) recommends its use in the form of a cream for strains, bruises, sports or accidental sprains, and joint and muscle pain. Also for the treatment of sprains, swellings, and haematomas after various closed injuries in order to improve motor function. 1

1 European Medicines Agency Committee on Herbal Medicinal Products (HMPC) Assessment report on Symphytum officinale L., radix 5 May 2015 EMA/ HMPC/572844/2009

Devil’s claw extract

Devil’s claw is a plant of the Pedaliaceae family that has been used for centuries by indigenous people throughout Africa for various purposes, such as external use as a painkiller. As a result of intensive research into the plant’s active ingredients, devil’s claw has been approved by the German Commission E (the German counterpart of the US Food and Drug Administration) for the treatment of musculoskeletal degenerative disorders and by the European Medicines Agency (EMA) as a traditional herbal medicine for the relief of small joint pain. 1

It is used to treat a variety of closed injuries and sports accidents, bruises, swelling and haemorrhage-related inflammation in order to improve motor function. 1

1 Blumenthal M. The Complete German Commission E Monographs. Austin, TX: American Botanical Council; 1998: 120-121. European Medicines Agency Evaluation of Medicines for Human Use, COMMUNITY HERBAL MONOGRAPH ON HARPAGOPHYTUM PROCUMBENS D.C. AND/OR HARPAGOPHYTUM ZEYHERIDECNE, RADIX, London, 10 January 2008

Devil’s claw extract

Devil’s claw is a plant of the Pedaliaceae family that has been used for centuries by indigenous people throughout Africa for various purposes, such as external use as a painkiller. As a result of intensive research into the plant’s active ingredients, devil’s claw has been approved by the German Commission E (the German counterpart of the US Food and Drug Administration) for the treatment of musculoskeletal degenerative disorders and by the European Medicines Agency (EMA) as a traditional herbal medicine for the relief of small joint pain. 1

1 1 Blumenthal M. The Complete German Commission E Monog- raphs. Austin, TX: Ame- rican Botanical Coun- cil; 1998:120-121. European Medici- nes Agency Evaluation of Medicines for Hu- man Use, COMMUNITY HERBAL MONOGRAPH ON HARPAGOPHY- TUM PROCUMBENS D.C. AND/OR HARPA- GOPHYTUM ZEYHERI DECNE, RADIX, Lon- don, 10 January 2008

Camphor

Menthol

Mountain arnica extract

Indian frankincense extract

Aloe vera leaf fluid

Aloe vera has been known for its healing properties for at least 6,000 years. There are more than 300 species of aloe plant, but Aloe barbadensis (also known as Aloe vera or Medical aloe) is the best known and is regularly used in the health and beauty industry for its healing properties.

Aloe gel, which is often found in creams and moisturisers, can help in skin care when applied topically. However, it is less well known that the salicylic acid in Aloe vera may also act as a painkiller. 1

1 https://www.every- dayhealth.com/dietnutrition/diet/ aloe-vera-benefits- risks-uses-more/ Fang X et al., Deter- mination of four sa- licylic acids in aloe by in vivo solid pha- se microextracti- on coupling with liquid chromatography-photodiode array detection., Talanta. 2018 Jul 1;184:520-526. doi: 10.1016/ j.talanta.2018.03.043. Epub 2018 Mar 15.

YXOR™ cream gel is a registered trademark of SynergoLAB.
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